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code:73-051
Key words: PDILT testis-specific protein disulfide isomerase homolog CALR3 ADAM3 Sperm Fetilization Protein folding Endoplasmic reticulum
Function: PDILT cooperates with the testis-specific calreticulin-like chaperone calsperin (CALR3) in the endoplasmic reticulum and plays an indispensable role in the disulfide-bond formation and folding of ADAM3. Pdilt(-/-) mice were male infertile because ADAM3 could not be folded properly and transported to the sperm surface without the PDILT/CALR3 complex.
Molecular mass:67759 Da with 588 amino acids. N-glucosylated
Applications:
1. Western blotting (1/1000 dilution)
2. Immunoprecipitation (1/100)
3. Immunohistochemistry、Frozen section (1/100-1/500)
Not tested for other applications.
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