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Code:70-105
Rad21 (631 aa 71 kDa) 2) is a cleavable component of cohesin complex involved in chromosome cohesion during cell cycle in DNA repair and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition this protein is cleaved by separase/ESPL1 and dissociates from chromatin allowing sister chromatids to segregate.
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