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Code:63-137
Schizosaccharomyces pombe Psm1 is a component of protein complex called cohesin which is required for sister chromatid cohesion during cell cycle and in DNA repair. The cohesion complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase the complex is cleaved and dissociates from chromatin allowing sister chromatids to segregate. S. pombe cohesin complexes are composed of the Psm1 and Psm3 heterodimer attached via their hinge domain Rad21 which link them and Psc3 which interacts with Rad21. Cohesin subunits are enriched in broad centromere region.
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