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Code:62-030
Storage: Shipped at 4℃ and stored at -20℃
Immunogen: Recombinant His-tagged Med11 protein (1-132) produced in E. coli
Reactivity: Reacts with S. cerevisiae Med11. Not tested with other species
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Applications: Western blotting (1/100-1/200). Not tested for other applications.
Form: Protein A affinity purified IgG 2 mg/ml in PBS 50% glycerol
Background: Component of the Mediator complex a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. The Mediator complex is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex (PIC) with RNA polymerase II and the general transcription factors. The essential MED11/22 heterodimer specifically functions in promoting stable PIC formation
Data Link UniProt Q99278 (MED11_YEAST) SGD S000004718. MED11.
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