62-027
Storage: Shipped at 4℃and stored at -20℃ for long period.
Immunogen: Recombinant His-tagged Ada2 protein (full-length; 1-434 aa) produced in E. coli
Reactivity: S. cerevisiae Ada2 protein. Not tested with other species
Applications: Western blotting (1/500-1/1000).
Form: Whole antiserum added with 0.1% sodium azide
Background: Ada2 functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA SALSA and ADA. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac H3K14ac H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). ADA preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B Ada2 consists of 434 amino acids with molecular mass of 50569 Da.
|