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製品番号：70-453
DDX18 protein (670aa 75.4KDa) is a putative ATP-dependent RNA helicase since it possesses a
DEAD box motif characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD).RNA helicases which may play a role in ribosome biogenesis. DDX18 acts as a cofactor for XPO1-mediated
nuclear export of incompletely spliced HIV-1 Rev RNAs. It was also involved in HIV-1 replication and
interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.
Applications
1) Western blotting (1000~ 2000 fold dilution)
2)Immunofluorescence staining (~500 fold dilution)
Not tested for other applications
Reactivity: Reacts with DDX18 of human and rodents.
Immunogen: Purified Human DDX18 fused with GST
Form:::: Undiluted anti rabbit serum added with 0.05 % sodium azide
Storage: Shipped at 4℃. Upon arrival aliquot and store at -20℃.
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