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製品番号:69-003
Storage： Shipped at 4°C and store at -20℃
Reactivity: Xenopus human
Applications
1) Western blotting (1/200-1/500 dilution)
2) Immunoprecipitation (1/100 dilution)
Immunogen: Synthetic peptide corresponding to C-terminal region of Xenopus Cdk1 protein (C-KSSLPDNQIRN) conjugated with KLH
Purity: Purified IgG
Form: 1.0 mg/ml in 1 x PBS and 50% glycerol
Background: Cdk1(cyclin-dependent kinase1) plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II. Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme while phosphorylation at Thr-161 activates it. Molecular mass is 34506
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