製品番号:62-152
Background: Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication repair recombination; RPA protects against inappropriate telomere recombination and upon telomere uncapping prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress RFA3 encodes 122 amino acids with molecular mass of 13816
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