抗Cdc48 (S. cerevisiae)抗体、ウサギポリクロ

Code:62-303

Background: Involved in spindle disassembly degradation of ubiquitinated proteins and protein export from the endoplasmic reticulum to the cytoplasm. Acts as a chaperone that collects ubiquitinated substrates. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway. Required for the proteasome-dependent processing/activation of MGA2 and SPT23 transcription factors leading to the subsequent expression of OLE1. Has an additional role in the turnover of OLE1 where it targets ubiquitinated OLE1 and other proteins to the ERAD.
Cdc48 consists of 836 amino acids with molecular mass of 92 kDa.

Applications
1) Western blotting (1/500~1/5000 dilution). Not tested for other applications.

Product: Whole antiserum added with 0.02% sodium azide.

Immunogen: Synthetic peptide HPDQYTKFGLSPSK (509~521) corresponding to 509~521 of Cdc48 protein.
Reactivity: S. cerevisiae Cdc48 protein not tested in other species

抗SLC2A3 / GLUT3 抗体 ラットモノクロ(#10)

74-200

Storage: Shipped at 4℃. Spin-down and store at -20℃.

Immunogen: Mouse sperm

Reactivity: Mouse SLC2A3/GLUT3. .

Applications
1. Western blotting (1/200-1/500)

Form: Purified monoclonal antibody (IgG) 1mg/ml in PBS 50% glycerol
filter-sterilized. Azide- and carrier-free.

Isotype: Rat IgG

Function: Facilitative glucose transporter. Probably a neuronal glucose
transporter.Abundant in sperm tail.

抗SCYL2 / CVAK104 抗体 ウサギポリクロ

製品番号:71-610

Background: Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293 probable serine/threonine-protein kinase that phosphorylates in vitro the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521 has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system

抗LBR(ヒト、マウス)抗体、affinity-purified

商品コード：70-301

Lamins は核膜タンパク質で核の構造と機能を保つのに重要である。Lamin B receptor (LBR) は核膜内膜に局在し、laminaとheterochromatin を核膜につなぎとめている (文献1)。Lamin B receptorはchromatinとlamin Bの相互作用を仲介していると思われる (文献2)。 Lamin とchromatinの相互作用はリン酸化によって制御されている。